Loctite Adhesive Selection Chart — Threadlockers, Gasket Makers, Retaining Compounds & Cleaners (222, 243, 262, 271, 277, 290, 518, 574, 638, 7063)

Reference manual hosted for technician access. 1 pages.
Brand
Henkel Loctite
Equipment
Anaerobic threadlockers, gasket makers, retaining compounds and surface preparation products
Document type
Selection guide
Revision
Henkel Loctite Industrial Adhesives — 2025 catalogue
Issued
2026-08-29
Pages
1
Format
PDF (application/pdf)

Loctite anaerobic product selection: threadlockers (222 low-strength, 243/2400 medium, 262 high, 271 permanent, 277 large-thread), retaining compounds (601, 638, 641, 648, 660, 680), gasket makers (510, 515, 518, 574, 5188), instant adhesives (401, 406, 480, 495, 496) and cleaners/primers (7063 general, 7649 primer, 7471 activator). Each product mapped to thread size, gap fill (mm), fixture and full-cure times, temperature range, strength and typical application. Cross-reference to Permabond, 3M, Anaerobic Adhesives (AA) and Vibra-TITE equivalents.

Loctite adhesive selection — threadlockers, gaskets, retaining, cleaners

Henkel's Loctite anaerobic range spans four functional families used across marine, oil & gas, wind, industrial machinery and vehicle assembly: threadlockers that prevent bolted joint loosening under vibration, retaining compounds that bond concentric parts (bearings on shafts, sleeves in bores), gasket makers that form in-place flange gaskets, and surface-preparation products (cleaners, primers, activators) that make the anaerobic cure work on inactive metals. Every Loctite anaerobic cures without oxygen once trapped between two close-fitting metal surfaces; the cure time depends on the substrate (active vs inactive) and the gap width. The tables below map each product to the joint size, gap, cure time and strength you need — and identify equivalents in the Permabond, 3M and Vibra-TITE ranges.

Threadlocker selection by thread size and strength

LoctiteColourStrengthThread rangeFixture (min)Full cure (h)Temp rangeRemovable
222PurpleLowM2-M201524-55 to +150 °CYes, hand tool
243BlueMediumM6-M201024-55 to +180 °CYes, hand tool
248 stickBlueMediumM6-M501024-55 to +150 °CYes, hand tool
262RedHighM6-M201024-55 to +150 °CYes with heat 250 °C
271RedVery HighM6-M251524-55 to +150 °CYes with heat 250 °C
272RedHigh, HTM6-M256072-55 to +230 °CYes with heat 260 °C
277RedHighM25-M563072-55 to +150 °CYes with heat 250 °C
290GreenMedium/High wickingM4-M12 pre-assembled1024-55 to +150 °CYes with heat 250 °C
2400BlueMedium, health-saferM6-M201024-55 to +150 °CYes, hand tool
2701GreenVery High, health-saferM6-M201524-55 to +150 °CYes with heat 250 °C

The blue-red-green colour code is Loctite's cross-catalogue shorthand: blue = medium strength, removable with hand tools (most common); red = high strength, needs heat to remove (permanent-in-service); purple = low, small-thread bolts and set-screws; green = wicking grade for pre-assembled fasteners. Pick 243 (blue, medium) as the default M6-M20 threadlocker; move to 271 for M25 and up, or to 277 for M25-M56 heavy studs. Loctite 290 is the answer to "the fasteners are already in place and I can't disassemble them" — its low-viscosity wicking grade capillary-flows down thread interstices under the head.

Retaining compound selection by gap width

LoctiteGradeMax diametric gapFixture (min)Full cure (h)Shear strength (N/mm²)Temp range
601High-strength, low viscosity0.10 mm102417-55 to +150 °C
603General, oil-tolerant0.10 mm102421-55 to +150 °C
620High temperature (230 °C)0.20 mm607217-55 to +230 °C
638High-strength, gap-fill0.25 mm102425-55 to +150 °C
641Removable service0.10 mm60247-55 to +150 °C
648High-strength, small gap0.15 mm102425-55 to +175 °C
660Gap-filling, quick repair0.50 mm102417-55 to +150 °C
680Very high strength0.25 mm152428-55 to +150 °C

Match the retaining compound to the diametric gap between the bore and the shaft — not the radial clearance. Use 638 as the workshop default for bearing races, keyways and slip-fit bushings up to 0.25 mm gap. Choose 660 for a "quick repair" service where the bore has been worn oversize and the gap is up to 0.50 mm. For high-temperature service (turbine casings, exhaust manifolds), 620 is the anaerobic that survives 230 °C; above that, thermal-cure epoxies replace anaerobics.

Gasket makers (form-in-place flange gaskets)

LoctiteTypeMax gapFixture (min)Full cure (h)Temp rangeTypical application
510Anaerobic, high-temp0.25 mm9024-55 to +200 °CExhaust manifolds, gearbox covers
515Anaerobic, general0.25 mm1524-55 to +150 °CPump housings, valve bonnets
518Anaerobic, flexible0.25 mm1524-55 to +150 °CGeneral industrial flanges; the workshop default
574Anaerobic, fast-cure0.50 mm1024-55 to +150 °CRough machined flanges, quick service
5188Anaerobic, gel0.50 mm1524-55 to +150 °CVertical flanges (won't run)
587 Blue Ultra RTVSilicone RTV6.35 mm60 (skin)24-55 to +260 °CWater pumps, oil pans; flexible
598 Black Ultra RTVSilicone RTV6.35 mm60 (skin)24-60 to +260 °COil-resistant flexible sealant

Loctite 518 is the industry default anaerobic gasket maker for machined metal flanges up to 0.25 mm gap — pump housings, gearbox covers, valve bonnets and hydraulic reservoirs. Loctite 574 is the fast-cure alternative for rough-machined castings or higher gap. When the flange gap exceeds 0.5 mm or the flange faces are non-metallic, switch to the 587/598 silicone RTVs. Loctite 518 equivalent products: Permabond A136, 3M ScotchWeld TE-030, Vibra-TITE 250 — all anaerobic gel gasket makers rated for similar service.

Cyanoacrylate (instant) adhesives

LoctiteTypeViscositySubstrateFixtureNotes
401General-purpose CALowWood, metal, rubber, plastic10-30 sWorkshop default
406Rubber & plastic CAVery lowElastomers, EPDM, NBR, plastics10-30 sBonds difficult rubbers
410Toughened CA (black)MediumMetals, magnets60 sImpact-resistant
480Toughened CA (black)MediumMetals60 sPeel/impact resistance
495General-purpose CALowMetal, rubber, plastic10-30 sAlternative to 401
496Metal-metal CAMediumSteel-steel bonding30 sFaster on steel

Surface preparation — cleaners, primers, activators

LoctiteTypePurposeApplication
SF 7063 (formerly 7063)Cleaner/degreaserGeneral surface cleaning before all Loctite anaerobics and CA400 ml aerosol; spray and wipe clean, allow to flash off
SF 7649 (formerly 7649)Activator N (primer)Accelerates anaerobic cure on stainless steel, aluminium, brass and passivated substratesSpray or brush, air-dry 30 s before adhesive
SF 7471 (formerly 7471)Activator T (primer)Fastest cure activator for anaerobic threadlockers on inactive metalsBrush or spray, air-dry 30 s; solvent-based
SF 7386 (formerly 7386)Cyanoacrylate activatorAccelerates CA cure on porous or acidic substratesSpray on one substrate, apply CA to other, mate
770 (Primer)Polyolefin primerPrepares PP, PE, PTFE for CA bondingBrush thin coat, air-dry 60 s

Loctite 7063 (also SF 7063 in newer packaging) is the general workshop cleaner used before every anaerobic and cyanoacrylate assembly — it removes light oils, machining coolant, oxidation and general shop grime without leaving residue that would poison the anaerobic cure. Loctite 7063 equivalent: Permabond Cleaner A905, 3M Adhesion Promoter AP111, MRO-approved petroleum-distillate degreasers. Do NOT substitute brake cleaner or generic parts cleaner for critical anaerobic joint prep — residual chlorinated solvent traces inhibit anaerobic polymerisation and reduce joint strength by 30-50 %.

Inactive substrates — when to prime

Loctite anaerobics cure quickly on active metals: carbon steel, cast iron, copper, brass and manganese-alloyed steels. They cure slowly (or not at all) on inactive metals: stainless steel, aluminium, zinc, cadmium plate, passivated coatings and plated fasteners. On inactive substrates:

Related products and references

Cure times, strength values and gap-fill capacity are Henkel Loctite published data at 22 °C on active carbon-steel substrates. Actual cure varies with temperature, substrate activity, gap width and primer/activator use. Loctite is a registered trademark of Henkel AG & Co. KGaA.

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Document provided as a reference for technicians servicing installed equipment. Trademarks and copyright remain the property of Henkel Loctite. Consult Henkel Loctite or your service representative for the current revision before performing any maintenance or warranty work.